What Is Apparent Is Not Always Real: Lessons from Lysine Requirement Studies in Adult Humans

P-value: What is and what is not

The misinterpretation and misuse of p-value have been increasing for decades. In March 2016, the American Statistical Association released a statement to warn about the use and interpretation of p-value. In this study, we provided a definition and discussion of p-value and emphasized the importance of its accurate interpretation.    

What is the Real Cause of Glaucoma?

Introduction: The term glaucoma refers to a group of diseases that have a characteristic optic neuropathy with associated visual field loss in common. Intraocular pressure has been considered to be the only causal factor for glaucoma and the only factor that can be manipulated to alter the course of the disease. But considering high intraocular pressure as the only factor responsible for glauco...

What is bright is not always gold.

To the Editor: The recent paper from Myerson et al1 on the “reliability” of formulae for calculation of echocardiographic left ventricular (LV) mass needs to be carefully considered. Quantitative echocardiography presents problems of reproducibility, but less than expected from initial studies performed without 2D guidance. There is evidence that the test-retest “error” of echocardiography is s...

health communication what it is and what is not

What You See is Not Always What You Sign

A fundamental aspect of computer systems is that displaying and signing a digital document are separate and unlinked processes. In addition, the same digital document can be displayed differently on different systems. As a consequence it is difficult to determine what exactly has been signed, both from the signer’s and the verifier’s point of view. This paper discusses how confusion about the m...